1.著書

 1) 小林一也 (2009)

 「プラナリア」

 鈴木載男編「身近な動物を用いた実験2」

 三共出版,1−20ページ ISBN-10: 4782705816 ISBN-13: 978-4782705810

       

 2) 小林一也・関井清乃(2017)

            「プラナリアたちの巧みな生殖戦略

            裳華房 ISBN 978-4-7853-5125-0


 3) Kobayashi, K., Kitano, T., Iwao, Y., Kondo, M. (2018)

            “Reproductive and Developmental Strategies: The Continuity of Life”

             Springer Japan, ISBN 978-4-431-56609-0

            



2.原著論文と総説(英文)
 33)Nobuyoshi Kumagai  Michio Kuroda , Tosei Hanai , Masaki Fujita , Takaaki Hino , Shunta Yorimoto , Sayaka Manta , Shuzo Nakagawa , Moe Yokoyama , Leon Tajima , Riku Ito , Hikaru Yamada , Kota Miura , Makoto Kashima , Katsushi Yamaguchi , Shuji Shigenobu  , Ryohei Furukawa , Kiyono Sekii , Kazuya Kobayashi
 "Identification of an innexin required for termination of the asexual state in planarian reproductive switching"
PLOS Genetics,Volume 21, Issue 11, November 18 2025


 32)Kiyono Sekii, Taro Watanabe, Riku Ito, Akitoshi Ypshikawa, Madoka Ichikawa-Seki, Kimitoshi Sakamoto, Kazuya Kobayashi
"Fractionation of a sex-inducing substance from flatworms using open-column chromatography and reverse-phase high-performance liquid chromatography"
STAR Protocols, Volume 4, Issue 4, 15 December 2023, 102625

 31) Kiyono Sekii, Soichiro Miyashita, Kentaro Yamaguchi, Ikuma Saito, Yuria Saito, Sayaka Manta, Masaki Ishikawa, Miyu Narita, Taro Watanabe, Riku Ito, Mizuki Taguchi, Ryohei Furukawa, Aoi Ikeuchi, Kayoko Matsuo, Goro Kurita, Takashi Kumagai, Sho Shirakashi, Kazuo Ogawa, Kimitoshi Sakamoto, Ryo Koyanagi, Kazuya kobayashi
"Sex-inducing effects toward planarians widely present among parasitic flatworms"
iScience Volume 26,Issue 1,20 January 2023 

 30) Makoto Kitamura, Hiroyuki Tanaka, Yurie Horiguchi, Sayaka Manta, Ikuma Saito, Hisashi Iwaya, Hikaru Okamoto, Nanna Nagao, Yumi Yanagihara, Yu Taguchi, Rei Tezuka, Takanobu Maezawa, Kiyono Sekii, Kazuya Kobayashi
“Sex-Inducing Activities of the Land Planarian Bipalium nobile Extract Fractions, Obtained Using Bioassay-Guided Fractionation, in the Freshwater Planarian Dugesia ryukyuensis" Zoological Science,38(6):544-557(2021)


 29)Osamu Kawase, Hisashi Iwaya, Yoshiya Asano, Hiromoto Inoue, Seiya Kudo, Motoki Sasahira, Nobuyuki Azuma, Daisuke Kondoh, Madoka Ichikawa-Seki, Xuenan Xuan, Kimitoshi Sakamoto, Hikaru Okamoto, Hinaki Nakadate, Wataru Inoue, Ikuma Saito, Miyu Narita,   

 Kiyono Sekii & Kazuya Kobayashi

“Identification of novel yolk ferritins unique to planarians: planarians supply aluminum rather than iron to vitellaria in egg capsules” Cell and Tissue Research 386,391-413(2021)


28) Takanobu Maezawa, Masaki Ishikawa, Kiyono Sekii, Go Nagamatsu, Ryohei Furukawa, Kazuya Kobayashi
”D-Tryptophan enhances the reproductive organ-specific expression of the amino acid transporter homolog Dr-SLC38A9 involved in the sexual induction of planarian Dugesia ryukyuensis.”,Zoological letters,vol.7:4 (2021)


27)Sekii,K.,Kobayashi,K.
“Sex-inducing substances terminate dormancy in planarian postembryonic reproductive development.”Advances in Invertebrate (Neuro) Endocrinology, vol 1:Phyla Other Than Arthropoda,Apple academic Press, 25-61(2020)

 26)Sekii, K., Yorimoto, S.,Okamoto, H., Nagao, N., Maezawa, T., Matsui, Y., Yamaguchi, K., Furukawa, R., shigenobu, S., Kobayashi, K.
“Transcriptomic analysis reveals differences in the regulation of amino acid metabolism in asexual and sexual planarians.” Scientific reports, vol.9: 6132 (2019)


25)Nakagawa, H., Sekii, K., Maezawa, T., Kitamura, M., Miyashita, S., Abukawa, M., Matsumoto, M., Kobayashi, K.
“A comprehensive comparison of Sex-inducing activity in asexual worms of the planarian Dugesia ryukyuensis: the crucial sex-inducing substance appears to be present in yolk glands in Tricladida.” Zoological letters, vol. 4: 14 (2018) 

  
24)Maezawa, T., Sekii, K., Ishikawa, M., Okamoto, H., Kobayashi, K.
“Reproductive strangies in planarians: Insights gained from the bioassay system for sexual induction in asexual Dugesia ryukyuensis worms, Springer Japan, Reproductive and Developmental Strategies: The Continuity of Life.”(2018)


23)Kobayashi, K., Maezawa, T., Tanaka, H., Onuki, H., Horiguchi,Y., Hirota, H., Ishida, T., Horiike, K., Agata, Y., Aoki, M., Hoshi, M.,  Matsumoto, M.

“The identification of ᴅ-tryptophan as a bioactive substance for postembryonic ovarian development in the planarian Dugesia ryukyuensis Scientific Reports, vol. 7: 45175 (2017)”



22)Okano, D., Ishida, S., Ishiguro, S., Kobayashi, K.

“Light and electron microscopic studies of the intestinal epithelium in Notoplana humilis (Platyhelminthes, Polycladida): the contribution of mesodermal / gastrodermal neoblasts to intestinal regeneration.”Cell and Tissue Research, on line (2015)

21)Maezawa, T., Tanaka, H., Nakagawa, H., Ono, M., Aoki, M., Matsumoto, M., Ishida, T., Horiike, K., Kobayashi, K.
“Planarian D-amino acid oxidase is involved in ovarian development during sexual induction.” Mechanisms of Development, vol. 132: 69-78 (2014)

20)Kobayashi, K., Nakagawa, H., Maezawa, T., Hoshi, M.

“Existence of two sexual races in the planarian species switching between asexual and sexual reproduction.” Zoological Science, vol. 29: 265-272 (2012)

19)Nakagawa, H., Ishizu, H., Chinone, A., Kobayashi, K., Matsumoto, M. 

 “The Dr-nanos gene is essential for germ cell specification in the planarian Dugesia ryukyuensis.” The International Journal of Developmental Biology, vol. 56: 165-171 (2012)

18)Nakagawa, H., Ishizu, H., Hasegawa, R., Kobayashi, K., Matsumoto, M. 

 “Drpiwi-1 is essential for germline cell formation during sexualization of the planarian Dugesia ryukyuensis.” Developmental Biology, vol. 361: 167-176 (2012)

17)Kobayashi, K., Hoshi, M. 

 “Sex-inducing effect of a hydrophilic fraction on reproductive switching in the planarian Dugesia ryukyuensis (Seriata, Tricladida).” Frontier in Zoology, vol. 8: 23 (2011)

16)Miyashita, H., Nakagawa, H., Kobayashi, K., Hoshi, M., Matsumoto, M.

“Effects of 17ß-estradiol and bisphenol A on the formation of reproductive organs in planarian.”The Biological Bulletin, vol. 220: 47-56 (2011)

15)Kobayashi, K., Arioka, S., Hoshi, M., Matsumoto, M 

“Production of asexual and sexual offspring in the triploid sexual planarian Dugesia ryukyuensis.”Integrative Zoology, vol. 4: 265-271 (2009)

14)Kobayashi, K., Hashiguchi, T., Ichikawa, T., Ishino, Y., Hoshi, M., Matsumoto, M. 

“Neoblast-enriched fraction rescues eye formation in eye-defective planarian ‘menashi’ Dugesia ryukyuensis.”Development, Growth & Differentiation, vol. 50: 689-696 (2008)

13)Kobayashi, K., Ishizu, H., Arioka, S., Cabrera, J. P., Hoshi, M., Matsumoto, M. 

“Production of diploid and triploid offspring by inbreeding of the triploid planarian Dugesia ryukyuensis.”Chromosoma, vol. 117, 289-296 (2008)

12)Hase, S., Kashiwagi, E., Kobayashi, K., Hoshi, M., Matsumoto, M. 

“Characterization of novel genes expressed specifically in the sexual organs of the planarian Dugesia ryukyuensis.”The International Journal of Developmental Biology, vol. 51: 345-349 (2007) 

11)Ishizuka, H., Maezawa, T., Kawauchi, J., Nodono, H., Hirano, Y., Nishimura, O., Nakagawa, H., Sekii, K., Tasaka, K., Tarui, H., Agata,K., Hoshi, M., Kobayashi, K., Sakakibara, Y., Matsumoto, M.

“The Dugesia ryukyuensis database as a molecular resource for studying switching of the reproductive system.”Zoological Science, vol. 24: 31-37 (2007)

10)Hase, S., Wakamatsu, K., Fujimoto, K., Inaba, A., Kobayashi, K., Matsumoto, M., Hoshi, M., Negishi, S.“Characterization of the pigment produced by the planarian, Dugesia ryukyuensis.” (2006)

9)Sato, Y., Kobayashi, K., Matsumoto, M., Hoshi, M., Negishi, S.

 “Comparative study of eye defective worm 'menashi' and regenerating wild-type in       planarian, Dugesia ryukyuensis.” Pigment Cell Research, vol. 18: 86-91 (2005)

8)Hase, S., Kobayashi, K., Koyanagi, R., Hoshi, M., Matsumoto, M.

 “Transcriptional pattern of a novel gene, expressing specifically after the point-of-no-return during sexualization, in planaria.”Development Genes and Evolution, vol. 212: 585-592 (2003)

7)Hoshi, M., Kobayashi, K., Arioka, S., Hase, S., Matsumoto, M. 

 “Switch from asexual to sexual reproduction in the planarian Dugesia ryukyuensis.”

   Integrative & Comparative Biology, vol. 43: 242-246 (2003)


6)Kobayashi, K., Arioka, S., Hoshi, M.

“Seasonal changes in the sexualization of the planarian Dugesia ryukyuensis.”

 Zoological Science, vol. 19: 1267-1278 (2002)


5)Kobayashi, K., Arioka, S., Hase, S., Hoshi, M.

“Signification of the sexualizing substance produced by the sexualized planarians.”

 Zoological Science, vol. 19: 667-672 (2002)


4)Kobayashi, K., Hoshi, M.

“Switching from asexual to sexual reproduction in the planarian Dugesia ryukyuensi: Change of the fissiparous capacity along with the sexualizing process.”

Zoological Science, vol. 19: 661-666 (2002)

3)Sato, K., Sugita, T., Kobayashi, K., Fujita, K., Fujii, T., Matsumoto, Y., Mikami, T., Nishizaki, N., Nishizuka, S., Shojima, K., Suda, M.,Takahashi, G., Himeno, H., Muto, A., Ishida, S.
“Localization of mitochondrial ribosomal RNA on the chromatoid bodies of marine planarian polyclad embryos.”Development, Growth & Differentiation, vol. 43: 107-114 (2001)

2)Kobayashi, K., Koyanagi, R., Matsumoto, M., Cabrera, J. P., Hoshi, H.

“Switching from asexual to sexual reproduction in the planarian Dugesia ryukyuensis: Bioassay system and basic description of sexualizing process.”

Zoological Science, vol. 16: 291-298 (1999)

1)Kobayashi, K., Koyanagi, R., Matsumoto, M., Hoshi, M. 

“Switching from asexual to sexual reproduction in the planarian Dugesia ryukyuensis.”

Invertebrate Reproduction & Development, vol. 36: 153-158 (1999)


3.総説と報告書(邦文)

 8)小林一也

 「本邦初報告となる海水棲マクロストマム2種について」

 金沢大学環日本海域環境研究センター臨海実験施設研究概要・年次報告 第7号, 20-23, ISSN 1348-4656 (2010)

 7)小林一也・松本緑

 「プラナリアの生殖様式転換機構と配偶子幹細胞」

 細胞工学 29, 670-674 (2010)

 6)小林一也・松本緑

 「プラナリアの生殖方法を無性生殖から有性生殖に転換させる化学物質」

 生物と化学 47, 672-673 (2009)

 5)小林一也

 「海水氷法により見つけ出した海に棲む扁形動物マクロストマム」

 うみうし通信 64, 4-5 (2009)

 4)松本緑・小林一也・星元紀

 「プラナリア生殖戦略転換における生殖細胞の起源」

 蛋白質核酸酵素 50, 541-545 (2005)

 3)小林一也・松本緑・星元紀

 「プラナリアにおける生殖戦略転換機構」

 蛋白質核酸酵素 49, 102-107 (2004)

 2) 小林一也

   「さきがけプログラム成果から(4): プラナリアにおける生殖戦略転換機構」

 科学新聞 第2959号(1)(2003)

 1)小林一也

  「プラナリアにおける無性生殖から有性生殖への転換機構」

   うみうし通信 22巻: 8-9 (1999)